I used to use Crossover for the few Windows applications that I still use, like Photoshop and Flash. Lately I found that Wine runs these applications better than Crossover Office and for free to boot! Crossover Office is a commercial product. In the course of looking up some Wine related items I found a little application named Wine-doors .

Wine-doors adds a repository style installer similar to the package managers found in Linux. What a great idea! Linux users are already used to this whole style of application management tools like Adept in Ubuntu so this just seems like a natural choice for Wine.

Here are some screenshots of Wine-doors in action installing Windows software on Ubuntu 7.10. There are a number of good applications in the repo, but I am not sure about the legalities - some things you may want to check into or avoid... Eitherway, Wine-doors is a program I highly recommend! 

Wine-door menu

Wine-door install

Wine-door application list

Wine-door installing Windows application

Wine running the newly installed application 

Also, if you need to run Adobe Photoshop plug-ins only and you're using Gimp in Linux I have pretty good luck using PSPI . Here's a screenshot .