I’m sure these will be hit or miss, but with a little work some Steam Windows games might run. If you want a unified gaming center on Linux with Steam for Windows support check out Lutris. Might be easier than pure Wine or Play On Linux. We will see.
Watch Dogs 2 is running without issue on Linux!
Now getting the Nvidia drivers working at full steam is another matter. I am using 415 version with a GTX 1060. These can be installed from the Ubuntu PPA:
Here’s a nice write up on linuxconfig.org